Symptoms
Hantavirus Symptoms
Hantavirus symptoms depend on the type of virus and the disease form it causes. The two main clinical forms are Hantavirus Pulmonary Syndrome (HPS/HCPS) and Hemorrhagic Fever with Renal Syndrome (HFRS).
Early symptoms can resemble the flu and typically appear 1–8 weeks after exposure to infected rodents or contaminated environments.
Incubation
Incubation Period
Symptoms do not usually appear immediately after exposure. For HPS, they typically occur 1–6 weeks after exposure, but may appear as early as one week and as late as eight weeks.
Sources: CDC — About Hantavirus · WHO — 2026 Outbreak Notice
Early Phase
Early Symptoms
Early symptoms can look similar to flu-like illness and may include:
- Fever
- Fatigue
- Muscle aches — especially thighs, hips, back, and shoulders
- Headache
- Dizziness
- Chills
- Nausea, vomiting, diarrhea
- Abdominal pain
Sources: CDC — About Hantavirus · CDC — Clinician Brief: HPS · WHO
HPS — Late Phase
Severe Respiratory Symptoms
After the early phase, HPS can progress to serious respiratory complications:
- Coughing
- Shortness of breath
- Difficulty breathing
- Chest tightness or pressure
- Fluid buildup in the lungs
- Low blood pressure
- Respiratory distress
HPS can be severe and may be fatal in nearly 4 out of 10 infected people who develop the syndrome.
Sources: CDC — About Hantavirus · CDC — Clinician Brief: HPS
HFRS
Hemorrhagic Fever with Renal Syndrome
HFRS is another form of hantavirus disease, mainly affecting the kidneys. It is more commonly associated with hantaviruses in Europe and Asia.
Symptoms may include:
- Sudden fever and intense headache
- Back and abdominal pain
- Chills and nausea
- Blurred vision
- Redness of the face and eyes
- Rash
In more severe cases:
- Low blood pressure and bleeding problems
- Acute kidney injury
- Reduced urine output
- Kidney failure
Sources: CDC — HFRS · ECDC — Factsheet on Orthohantavirus Infections
⚠ Urgent
When to Seek Medical Help
Seek medical help urgently if you develop any of the following after possible contact with rodents, rodent droppings, urine, saliva, or contaminated dust:
- Fever with severe weakness or muscle pain
- Coughing or shortness of breath
- Chest tightness
- Signs of kidney problems
Tell your doctor about any recent exposure to rodents or cleaning of basements, garages, sheds, cabins, storage rooms, or other places where rodents may have been present.
Source: CDC — Clinical Overview of Hantavirus
Summary
Short Summary
Hantavirus infection can begin with flu-like symptoms such as fever, fatigue, muscle aches, headache, chills, nausea, vomiting, diarrhea, and abdominal pain. In severe cases, it can progress to coughing, shortness of breath, respiratory distress, low blood pressure, or kidney problems.
Anyone with symptoms after possible rodent exposure should contact a healthcare professional as soon as possible.
Sources & References
Information for awareness only. For diagnosis and treatment, consult medical professionals and official public health guidance.